Vaping-related illnesses in the U.S. are still rising, though at a slightly slower pace.

Health officials of Thursday said there have been 1,479 cases and at least 33 deaths in the mysterious outbreak.

The Centers for Disease Control and Prevention has been releasing new case counts each week. The latest jump — 180 cases — was the lowest increase since mid-September. But CDC officials say there’s no indication that the outbreak is waning.

The latest update came as a new study suggests that vaping e-liquids, specifically propylene glycol and glycerin, may lead to some inflammation in the lungs – but more research is needed to determine just how much inflammation may occur over a prolonged period of time.

The study, published in the journal Cancer Prevention Research on Wednesday, found that in people who had never smoked, after using e-cigarettes just twice daily for a month, levels of propylene glycol in their system was linked with changes in inflammatory cell counts in their lungs, although the magnitude of changes was small.

“Although limited by study size and duration, this is the first experimental demonstration of an impact of e-cig use on inflammation in the human lung among never-smokers,” the researchers wrote.

New study is first ‘demonstration’ to link vaping e-liquids with lung inflammation

The outbreak appears to have started in March. Symptoms of the illness include severe shortness of breath, fatigue, and chest pain. No single ingredient, electronic cigarette or vaping device has been linked to all the illnesses.

Most who got sick said they vaped products containing THC, the high-inducing ingredient in marijuana. Investigators say they are increasingly focused on black-market THC products.

About 1 in 10 of the outbreak cases said they used only nicotine but that percentage has been falling. It was 13% last week. In some cases, people who initially claimed they had used only nicotine admitted later they had vaped THC.

Until a cause is pinpointed, the CDC is advising Americans to refrain from vaping.

Forty-nine states and one U.S. territory have reported illnesses. Only Alaska has not seen a case. The vast majority of cases are people in their teens, 20s or early 30s, according to the CDC.

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